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KMID : 0616120190500030155
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Korean Journal of Pharmacognosy
2019 Volume.50 No. 3 p.155 ~ p.158
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Validation and Content Analysis of Cornusiin B Isolated from Cornus alba
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Park Dong-Hui
Yin Jun
Wang Hye-Soo
Kim Min
Kim Min-Ji
Lee Eun-Kyeng
Lee Min-Won
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Abstract
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Cornus alba (CA) geographically distributes in Korea, Japan, Northeast China and Russia. The cornus species have been used traditionally as anti-inflammatory, hemostatic and diuretic in Korea. Previously, it was reported CA and its separated components have excellent antioxidant, anti-inflammatory and anti-prostate cancer efficacy. Present work, the validation and content determination was tried on the ellagitannin, cornusiin B which were isolated from the CA by using high-performance liquid chromatography (HPLC). As a result, the content of cornusiin B were 3.07% in ethanolic extract of CA.
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KEYWORD
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Validation, Content, Cornus alba, Cornusiin B, HPLC
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